GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
THYM | cis | rs911119 | 1 | rs13039536 | chr20:23612305 | CST9 | chr20:23583049-23586610:- | -0.51 | -4.71 | 8.44E-6 | Chronic kidney disease |
THYM | cis | rs911119 | 1 | rs13041070 | chr20:23614261 | CST9 | chr20:23583049-23586610:- | -0.51 | -4.71 | 8.44E-6 | Chronic kidney disease |
THYM | cis | rs10935120 | 1 | rs13059720 | chr3:134242021 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.13 | 1.58E-12 | Height |
THYM | cis | rs10935120 | 1 | rs13059720 | chr3:134242021 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.87 | 6.33E-8 | Height |
THYM | cis | rs9876781 | 1 | rs13069724 | chr3:48478039 | TREX1 | chr3:48501186-48509043:+ | -0.28 | -4.14 | 7.54E-5 | Longevity |
THYM | cis | rs9876781 | 1 | rs13071337 | chr3:48438189 | TREX1 | chr3:48501186-48509043:+ | -0.28 | -4.38 | 3.02E-5 | Longevity |
THYM | cis | rs10935120 | 1 | rs13071551 | chr3:134310867 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.1 | 1.9E-12 | Height |
THYM | cis | rs10935120 | 1 | rs13071551 | chr3:134310867 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.93 | 4.96E-8 | Height |
THYM | cis | rs13073838 | 1 | rs13073838 | chr3:74627703 | CNTN3 | chr3:74311722-74570343:- | 0.47 | 4.82 | 5.5E-6 | Economic and political preferences |
THYM | cis | rs3796352 | 1 | rs13076033 | chr3:52898427 | ITIH4 | chr3:52847007-52866554:- | -0.52 | -4.62 | 1.21E-5 | Immune reponse to smallpox (secreted IL-2) |
THYM | cis | rs9876781 | 1 | rs13076076 | chr3:48479039 | TREX1 | chr3:48501186-48509043:+ | -0.29 | -4.26 | 4.8E-5 | Longevity |
THYM | cis | rs10935120 | 1 | rs13081177 | chr3:134289860 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.13 | 1.58E-12 | Height |
THYM | cis | rs10935120 | 1 | rs13081177 | chr3:134289860 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.87 | 6.33E-8 | Height |
THYM | cis | rs10935120 | 1 | rs13081688 | chr3:134259954 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.13 | 1.58E-12 | Height |
THYM | cis | rs10935120 | 1 | rs13081688 | chr3:134259954 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.87 | 6.33E-8 | Height |